Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001020)
Formula
CYP3A7 ...
SVG example
Oxidation
Reactant Felbamate Product 2-hydroxyfelbamate
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A7 (CYP3A7) DME Info
Cytochrome P450 2E1 (CYP2E1) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001018 Felbamate 2-Phenyl-1,3-propanediol monocarbamate Hydrolysis - Esterase Hydrolysis Felbamate [1]
MR001019 Felbamate p-hydroxyfelbamate Unclear Felbamate [2]
References
1 Felbamate-induced apoptosis of hematopoietic cells is mediated by redox-sensitive and redox-independent pathways Epilepsy Res. 2002 Jan;48(1-2):57-69. doi: 10.1016/s0920-1211(01)00320-5.
2 DrugBank(Pharmacology-Metabolism)Felbamate

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