Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001341)
Formula Reactant M9 (Ketoconazole) Product Ketoconazole iminium ion
Reactant Info Product Info
Metabolic Type Other reaction - Dehydration
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001356 Ketoconazole M9 (Ketoconazole) Oxidation - Hydoxylation Ketoconazole [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001340 M9 (Ketoconazole) M10 (Ketoconazole) Oxidation - N-Dealkylation Ketoconazole [1]
MR001342 M9 (Ketoconazole) M12 (Ketoconazole) Oxidation - Oxidation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

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