Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001463)
Formula Reactant Levobunolol Product Hydroxy-LB
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001462 Levobunolol Levobunolol metabolite M10 Oxidation - Oxidation Levobunolol [1]
MR001461 Levobunolol Levobunolol metabolite M11 Reduction - Reduction Levobunolol [1]
MR001466 Levobunolol Levobunolol metabolite M12 Oxidation - Dihydroxylation Levobunolol [1]
MR001465 Levobunolol Levobunolol metabolite M13 Oxidation - Monohydroxylation Levobunolol [1]
MR001464 Levobunolol Levobunolol metabolite M9 Oxidation - Monohydroxylation Levobunolol [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001459 Hydroxy-LB Levobunolol metabolite M14 Conjugation - Acetylation Levobunolol [1]
MR001460 Hydroxy-LB Levobunolol metabolite M15 Conjugation - Acetylation Levobunolol [1]
MR001457 Hydroxy-LB Levobunolol metabolite M2 Conjugation - Glucuronidation Levobunolol [1]
MR001458 Hydroxy-LB Levobunolol metabolite M5 Conjugation - Glucuronidation Levobunolol [1]
References
1 Ocular Metabolism of Levobunolol: Historic and Emerging Metabolic Pathways Drug Metab Dispos. 2016 Aug;44(8):1304-12. doi: 10.1124/dmd.116.070458.

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