Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001497)
Formula
SVG example
Methylation
Reactant Norepinephrine Product Epinephrine E
Reactant Info Product Info
Metabolic Enzyme Phenylethanolamine N-methyltransferase (PNMT) DME Info
Metabolic Type Conjugation - Methylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010710 Norepinephrine 3-Methoxy-4-Hydroxyphenylglycol sulfate Unclear - Unclear Norepinephrine [1]
MR010709 Norepinephrine Norepinephrine sulfate Unclear - Unclear Norepinephrine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007738 Dipivefrin Epinephrine Hydrolysis - Hydrolysis dipivefrin [2]
References
1 Mesenteric organ production, hepatic metabolism, and renal elimination of norepinephrine and its metabolites in humans
2 Site of ocular hydrolysis of a prodrug, dipivefrin, and a comparison of its ocular metabolism with that of the parent compound, epinephrine

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