Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001588)
Formula Reactant Lumiracoxib metabolite M11 Product Lumiracoxib metabolite M3
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001584 Lumiracoxib metabolite M21 Lumiracoxib metabolite M11 Oxidation - Oxidation Lumiracoxib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001587 Lumiracoxib metabolite M11 Lumiracoxib metabolite M15 Unclear Lumiracoxib [1]
MR001586 Lumiracoxib metabolite M11 Lumiracoxib metabolite M5 Oxidation - Hydroxylation Lumiracoxib [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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