Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001603)
Formula
CYP2C19 ...
SVG example
Hydroxylation
Reactant Lumiracoxib Product Lumiracoxib metabolite M23
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001602 Lumiracoxib Lumiracoxib metabolite M21 Oxidation - Methyl-Hydroxylation Lumiracoxib [1]
MR001604 Lumiracoxib Lumiracoxib metabolite M24 Conjugation - Glucuronidation Lumiracoxib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001600 Lumiracoxib metabolite M23 Lumiracoxib metabolite M22 Conjugation - Glucuronidation Lumiracoxib [1]
MR001599 Lumiracoxib metabolite M23 Lumiracoxib metabolite M25 Unclear Lumiracoxib [1]
MR001598 Lumiracoxib metabolite M23 Lumiracoxib metabolite M9 Unclear Lumiracoxib [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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