Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001614)
Formula
SVG example
N-Demethylation
Reactant Medifoxamine Product N-desmethylmedifoxamine
Reactant Info Product Info
Metabolic Type Oxidation - N-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001616 Medifoxamine Acidic medifoxamine Unclear Medifoxamine [1]
MR001617 Medifoxamine Hydroxymedifoxamine Oxidation - Hydroxylation Medifoxamine [2]
MR001615 Medifoxamine N-oxide medifoxamine Oxidation - N-Oxidation Medifoxamine [3]
References
1 Solid-phase extraction of diltiazem and its metabolites from plasma prior to high-performance liquid chromatography J Chromatogr. 1990 Jun 29;528(2):542-6. doi: 10.1016/s0378-4347(00)82416-0.
2 Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors J Clin Invest. 1990 Aug;86(2):385-91. doi: 10.1172/JCI114723.
3 Simple and practical high-performance liquid chromatographic assay of propofol in human blood by phenyl column chromatography with electrochemical detection J Chromatogr. 1990 Jun 29;528(2):537-41. doi: 10.1016/s0378-4347(00)82415-9.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.