Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001658)
Formula
SVG example
Acetylation
Reactant 4-amino-antipyrine (AA) Product 4-acetyl-amino-antipyrine (AAA)
Reactant Info Product Info
Metabolic Type Conjugation - Acetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001655 N-Desmethylaminopyrine 4-amino-antipyrine (AA) Oxidation - N-Demethylation Metamizole sodium [1], [2]
MR001657 4-formyl-amino-antipyrine (FAA) 4-amino-antipyrine (AA) Oxidation - N-Demethylation Metamizole sodium [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001659 4-amino-antipyrine (AA) Arachidonoyl-4-aminoantipyrine (ARA-4-AA) Unclear Metamizole sodium [1], [2]
References
1 Metamizole (Dipyrone) and the Liver: A Review of the Literature J Clin Pharmacol. 2019 Nov;59(11):1433-1442. doi: 10.1002/jcph.1512.
2 Clinical pharmacokinetics of dipyrone and its metabolites Clin Pharmacokinet. 1995 Mar;28(3):216-34. doi: 10.2165/00003088-199528030-00004.

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