Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001791)
Formula
	Reactant	17-desacetylnorgestimate	Product	Norgestrel
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001793	Norgestimate	17-desacetylnorgestimate	Oxidation - Deacetylation	Norgestimate	[1], [2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001792	Norgestrel	Norgestrel glucuronide metabolite	Conjugation - O-Glucuronidation	Norgestimate	[3]

References
1	Metabolism of norgestimate by human gastrointestinal mucosa and liver microsomes in vitro J Steroid Biochem Mol Biol. 1991 Apr;38(4):497-503. doi: 10.1016/0960-0760(91)90338-6.
2	Metabolite identification, reaction phenotyping, and retrospective drug-drug interaction predictions of 17-deacetylnorgestimate, the active component of the oral contraceptive norgestimate. Drug Metab Dispos. 2017 Jun;45(6):676-685.
3	DrugBank(Pharmacology-Metabolism)Norgestimate

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