Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001939)
Formula
SVG example
Sulfation
Reactant Pantoprazole Sodium Product Pantoprazole sulfate
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 1A1 (SULT1A1) DME Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001938 Pantoprazole Sodium Desmethylpantoprazole Oxidation - Demethylation Pantoprazole Sodium [1]
MR001940 Pantoprazole Sodium Pantoprazole Sulfone Reduction - Reduction Pantoprazole Sodium [2]
References
1 Proton pump inhibitors: from CYP2C19 pharmacogenetics to precision medicine. Expert Opin Drug Metab Toxicol. 2018 Apr;14(4):447-460.
2 Interaction of proton pump inhibitors with cytochromes P450: consequences for drug interactions. Yale J Biol Med. 1996 May-Jun;69(3):203-9.

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