Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001992)
Formula
SVG example
Reduction
Reactant Pergolide mesylate Product Pergolide sulfoxide
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001990 Pergolide mesylate N-Despropyl Pergolide Oxidation - Demethylation Pergolide mesylate [1]
MR001991 Pergolide mesylate Pergolide sulfone Reduction - Reduction Pergolide mesylate [2]
References
1 Anti-Parkinson's disease drugs and pharmacogenetic considerations Expert Opin Drug Metab Toxicol. 2013 Jul;9(7):859-74. doi: 10.1517/17425255.2013.789018.
2 Dopamine agonist activities of pergolide, its metabolites, and bromocriptine as measured by prolactin inhibition, compulsive turning, and stereotypic behavior Arzneimittelforschung. 1993 Mar;43(3):281-6.

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