Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR002065)
Formula
	Reactant	Piroxicam		Product	Cyclodehydrated metabolite
	Reactant	Reactant Info		Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002064	Piroxicam	5'-hydroxypiroxicam	Oxidation - 5'-Hydroxylation	Piroxicam	[1], [2]
MR002066	Piroxicam	Carboxybenzothiazine metabolite	Unclear	Piroxicam	[1], [2]
MR008910	Piroxicam	5'-Hydroxypiroxicam	Unclear - Unclear	Ampiroxicam	[3]

References
1	In vivo Piroxicam Metabolites: Possible Source for Synthesis of Central Nervous System (CNS) Acting Depressants Cent Nerv Syst Agents Med Chem. 2017;17(3):172-177. doi: 10.2174/1871524917666161111093759.
2	Metabolism of piroxicam by laboratory animals Drug Metab Dispos. 1981 Mar-Apr;9(2):114-8.
3	Pharmacokinetic drug interactions between ampiroxicam and sulfaphenazole in rats

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