| General Information of This Metabolic Reaction (MR) (ID:
MR002075) |
| Formula |
Reactant |
5-hydroxypomalidomide |
Product |
5-hydroxypomalidomide glucuronide |
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Reactant Info
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Product Info
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Metabolic Type
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Conjugation
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Glucuronidation
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| Other MR(s) Related to The Reactant of This MR |
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Other MR(s) That Produce The Reactant of This MR
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| References |
| 1 |
Absorption, metabolism and excretion of [14C]pomalidomide in humans following oral administration Cancer Chemother Pharmacol. 2013 Feb;71(2):489-501. doi: 10.1007/s00280-012-2040-6.
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| 2 |
Pomalidomide: evaluation of cytochrome P450 and transporter-mediated drug-drug interaction potential in vitro and in healthy subjects. J Clin Pharmacol. 2015 Feb;55(2):168-78.
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| 3 |
Metabolic profiles of pomalidomide in human plasma simulated with pharmacokinetic data in control and humanized-liver mice Xenobiotica. 2017 Oct;47(10):844-848. doi: 10.1080/00498254.2016.1247218.
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