Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002115)
Formula
SVG example
Reactant 6beta-hydroxy-prednisolone(M-VI) Product 6beta,11beta,17alpha,21-tetrahydroxy-5xi-pregn-1-en-3,20-dione (M-XIV)
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002127 Prednisolone 6beta-hydroxy-prednisolone(M-VI) Oxidation - Hydroxylation Prednisolone [1]
MR002779 Prednisolone 6beta-hydroxy-prednisolone(M-VI) Unclear Prednisone [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002116 6beta-hydroxy-prednisolone(M-VI) 6beta,11beta,17alpha,20alpha,21-pentahydroxypregnan-1,4-diene-3-one (M-IX) Unclear Prednisolone [1]
MR002117 6beta-hydroxy-prednisolone(M-VI) 6beta,11beta,17alpha,20beta,21-pentahydroxypregnan-1,4-diene-3-one (M-VIII) Unclear Prednisolone [1]
MR002763 6beta-hydroxy-prednisolone(M-VI) 6beta,11beta,17alpha,20alpha,21-pentahydroxypregnan-1,4-diene-3-one (M-IX) Unclear Prednisone [1]
MR002764 6beta-hydroxy-prednisolone(M-VI) 6beta,11beta,17alpha,20beta,21-pentahydroxypregnan-1,4-diene-3-one (M-VIII) Unclear Prednisone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002119 6beta,11beta,17alpha,20alpha,21-pentahydroxy-5xi-pregn-1-en-3-one (M-XVI) 6beta,11beta,17alpha,21-tetrahydroxy-5xi-pregn-1-en-3,20-dione (M-XIV) Unclear Prednisolone [1]
MR002121 6beta,11beta,17alpha,20beta,21-pentahydroxy-5xi-pregn-1-en-3-one (M-XV) 6beta,11beta,17alpha,21-tetrahydroxy-5xi-pregn-1-en-3,20-dione (M-XIV) Unclear Prednisolone [1]
MR002766 6beta,11beta,17alpha,20alpha,21-pentahydroxy-5xi-pregn-1-en-3-one (M-XVI) 6beta,11beta,17alpha,21-tetrahydroxy-5xi-pregn-1-en-3,20-dione (M-XIV) Unclear Prednisone [1]
MR002768 6beta,11beta,17alpha,20beta,21-pentahydroxy-5xi-pregn-1-en-3-one (M-XV) 6beta,11beta,17alpha,21-tetrahydroxy-5xi-pregn-1-en-3,20-dione (M-XIV) Unclear Prednisone [1]
References
1 Detection and characterization of prednisolone metabolites in human urine by LC-MS/MS J Mass Spectrom. 2015 Mar;50(3):633-42. doi: 10.1002/jms.3571.
2 Pharmacokinetic and pharmacoimmunodynamic interactions between prednisolone and sirolimus in adrenalectomized rats. J Pharmacokinet Biopharm. 1999 Feb;27(1):1-21.

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