Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002125)
Formula
SVG example
Reactant Prednisolone Product 17alpha,21-dihydroxy-pregnan-1,4,6-trien-3,11,30-trione (M-XVII)
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002123 Prednisolone 20alpha-dihydro-prednisolone (M-III) Unclear Prednisolone [1]
MR002128 Prednisolone 20alpha-dihydro-prednisone (M-V) Unclear Prednisolone [1]
MR002124 Prednisolone 20beta-dihydro-prednisolone (M-II) Unclear Prednisolone [1]
MR002126 Prednisolone 6alpha-hydroxy-prednisolone (M-VII) Oxidation - Hydroxylation Prednisolone [1]
MR002127 Prednisolone 6beta-hydroxy-prednisolone(M-VI) Oxidation - Hydroxylation Prednisolone [1]
MR002122 Prednisolone Delta6-prednisolone (M-XI) Unclear Prednisolone [1]
MR002129 Prednisolone Prednisone Unclear Prednisolone [1]
MR002779 Prednisolone 6beta-hydroxy-prednisolone(M-VI) Unclear Prednisone [2]
MR002776 Prednisolone 20alpha-dihydro-prednisolone (M-III) Unclear Prednisone [1]
MR002777 Prednisolone 20beta-dihydro-prednisolone (M-II) Unclear Prednisone [1]
MR002778 Prednisolone 6alpha-hydroxy-prednisolone (M-VII) Unclear Prednisone [1]
MR002775 Prednisolone Delta6-prednisolone (M-XI) Unclear Prednisone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002769 Prednisone 17alpha,21-dihydroxy-pregnan-1,4,6-trien-3,11,30-trione (M-XVII) Unclear Prednisone [1]
References
1 Detection and characterization of prednisolone metabolites in human urine by LC-MS/MS J Mass Spectrom. 2015 Mar;50(3):633-42. doi: 10.1002/jms.3571.
2 Pharmacokinetic and pharmacoimmunodynamic interactions between prednisolone and sirolimus in adrenalectomized rats. J Pharmacokinet Biopharm. 1999 Feb;27(1):1-21.

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