Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002159)
Formula
SVG example
Reactant Azoprocarbazine Product Methylazoxyprocarbazine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002165 Procarbazine Azoprocarbazine Unclear Procarbazine [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002160 Azoprocarbazine Azoxy-1-procarbazine Unclear Procarbazine [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002161 Methylazoxyprocarbazine Aldehyde derivative Unclear Procarbazine [2], [3]
References
1 Tumour cytochrome P450 and drug activation. Curr Pharm Des. 2002;8(15):1335-47.
2 Plasma kinetics of procarbazine and azo-procarbazine in humans Anticancer Drugs. 2006 Jan;17(1):75-80. doi: 10.1097/01.cad.0000181591.85476.aa.
3 Quantitative analysis of procarbazine, procarbazine metabolites and chemical degradation products with application to pharmacokinetic studies J Chromatogr. 1982 May 14;229(2):397-407. doi: 10.1016/s0378-4347(00)84282-6.

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