Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002208)
Formula	Reactant	Rucaparib M323 metabolite	Product	Rucaparib metabolite M337C
Formula	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Conjugation - N-Methylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002210	Rucaparib	Rucaparib M323 metabolite	Oxidation - Oxidation	Rucaparib	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002207	Rucaparib M323 metabolite	Rucaparib M337a metabolite	Conjugation - N-Methylation	Rucaparib	[1]

References
1	Evaluation of absorption, distribution, metabolism, and excretion of [(14)C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors Invest New Drugs. 2020 Jun;38(3):765-775. doi: 10.1007/s10637-019-00815-2.

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