| General Information of This Metabolic Reaction (MR) (ID:
MR002225) |
| Formula |
Reactant |
Secnidazole |
Product |
Glucuronide conjugates of secnidazole |
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Reactant Info
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Product Info
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Metabolic Enzyme
|
UDP-glucuronyltransferase (UGT)
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DME Info
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Metabolic Type
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Conjugation
-
Conjugation
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| Other MR(s) Related to The Reactant of This MR |
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Other MR(s) That Metabolize The Reactant of This MR
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| References |
| 1 |
In vitro metabolic profile and drug-drug interaction assessment of secnidazole, a high-dose 5-nitroimidazole antibiotic for the treatment of bacterial vaginosis Pharmacol Res Perspect. 2020 Aug;8(4):e00634. doi: 10.1002/prp2.634.
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| 2 |
Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis Drugs. 1996 Apr;51(4):621-38. doi: 10.2165/00003495-199651040-00007.
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