Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002248)
Formula Reactant Sibutramine metabolite M1 Product Sibutramine metabolite M5
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation; Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002250 Sibutramine Sibutramine metabolite M1 Oxidation - Demethylation Sibutramine [1], [2]
References
1 Sibutramine: a serotonin-norepinephrine reuptake-inhibitor for the treatment of obesity. Ann Pharmacother. 1999 Sep;33(9):968-78.
2 Metabolic analysis of the illegal analogues of anti-obesity drugs using LC-Q-TOF-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jan 15;1163:122502. doi: 10.1016/j.jchromb.2020.122502.

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