Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002328)
Formula Reactant Methyl Tadalafil catechol Product Methyl Tadalafil catechol glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002327 Tadalafil catechol Methyl Tadalafil catechol Conjugation - Methylation Tadalafil [1]
References
1 Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats Pharmaceutics. 2019 Jul 20;11(7):354. doi: 10.3390/pharmaceutics11070354.

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