Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002339)
Formula Reactant Tasimelteon metabolite M13 Product Tasimelteon metabolite M11
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002340 Tasimelteon Tasimelteon metabolite M13 Oxidation - Hydroxylation Tasimelteon [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002338 Tasimelteon metabolite M13 Tasimelteon metabolite M9 Unclear Tasimelteon [1]
References
1 Clinical assessment of drug-drug interactions of tasimelteon, a novel dual melatonin receptor agonist. J Clin Pharmacol. 2015 Sep;55(9):1004-11.

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