Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002441)
Formula
	Reactant	4'-hydroxytrazodone	Product	Trazodone hydrochloride MW
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002443	Trazodone hydrochloride	4'-hydroxytrazodone	Oxidation - Hydroxylation	Trazodone hydrochloride	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002440	4'-hydroxytrazodone	Trazodone hydrochloride M6	Conjugation - Glutathione Conjugation	Trazodone hydrochloride	[1]

References
1	Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4. Chem Biol Interact. 2005 Jun 30;155(1-2):10-20.

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