Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002506)
Formula Reactant Vemurafenib intermediary metabolite Product Secondary metabolite of vemurafenib alternative
Reactant Info Product Info
Metabolic Type Oxidation - Dehalogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002510 Vemurafenib Vemurafenib intermediary metabolite Hydrolysis - Hydrolysis Vemurafenib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002507 Vemurafenib intermediary metabolite Secondary metabolite of vemurafenib Hydrolysis - Hydrolysis Vemurafenib [1]
References
1 A single-dose mass balance and metabolite-profiling study of vemurafenib in patients with metastatic melanoma Pharmacol Res Perspect. 2015 Mar;3(2):e00113. doi: 10.1002/prp2.113.

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