Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002561)
Formula
SVG example
7-O-Demethylation
Reactant RPR123142 Product RP56976
Reactant Info Product Info
Metabolic Type Oxidation - 7-O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002575 Cabazitaxel RPR123142 Oxidation - 10-O-Demethylation Cabazitaxel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002566 RPR112698 RP56976 Oxidation - 10-O-Demethylation Cabazitaxel [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002562 RP56976 RPR104952 Oxidation - Hydroxylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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