Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002564)
Formula Reactant RPR111026 Product Cabazitaxel metabolite M09b
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002570 Cabazitaxel metabolite M08b RPR111026 Oxidation - 10-O-Demethylation Cabazitaxel [1]
MR002563 RPR104952 RPR111026 Oxidation - Hydroxylation Cabazitaxel [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002565 RPR111026 RPR104943 Oxidation - Hydroxylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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