Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002568)
Formula Reactant Cabazitaxel metabolite M07 Product RPR104952
Reactant Info Product Info
Metabolic Type Oxidation - 10-O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002567 RPR112698 Cabazitaxel metabolite M07 Oxidation - Hydroxylation Cabazitaxel [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002569 Cabazitaxel metabolite M07 Cabazitaxel metabolite M08b Oxidation - Hydroxylation Cabazitaxel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002562 RP56976 RPR104952 Oxidation - Hydroxylation Cabazitaxel [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002563 RPR104952 RPR111026 Oxidation - Hydroxylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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