Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002578)
Formula Reactant Cabazitaxel Product RPR130523
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002577 Cabazitaxel Cabazitaxel metabolite M1 Oxidation - Hydroxylation Cabazitaxel [1]
MR002576 Cabazitaxel RPR112698 Oxidation - 7-O-Demethylation Cabazitaxel [1]
MR002575 Cabazitaxel RPR123142 Oxidation - 10-O-Demethylation Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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