Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002590)
Formula
SVG example
N-Glucuronidation
Reactant Carbamazepine Product Carbamazepine N-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - N-Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002588 Carbamazepine 10,11-Epoxycarbamazepine Oxidation - 10,11-Epoxidation Carbamazepine [1]
MR002589 Carbamazepine 3-hydroxycarbamazepine Oxidation - 3-Hydroxylation Carbamazepine [1]
MR002587 Carbamazepine Carbamazepine 2,3-epoxide Unclear Carbamazepine [1]
References
1 Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood Epilepsia. 1995 Mar;36(3):241-8. doi: 10.1111/j.1528-1157.1995.tb00991.x.

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