Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002758)
Formula
SVG example
Hydroxylation
Reactant Prednisolone 21-ethylcarbonate Product Prednisolone
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002757 Prednisolone 17-ethylcarbonate Prednisolone 21-ethylcarbonate Other reaction - Nonenzymatic Transformation Prednicarbate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002774 Prednisone Prednisolone Unclear Prednisone [2]
References
1 Prednicarbate biotransformation in human foreskin keratinocytes and fibroblasts Pharm Res. 1997 Jun;14(6):793-7. doi: 10.1023/a:1012162708675.
2 Detection and characterization of prednisolone metabolites in human urine by LC-MS/MS J Mass Spectrom. 2015 Mar;50(3):633-42. doi: 10.1002/jms.3571.

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