Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR002837)
Formula	UGT1A4 Glucuronidation
	Reactant	Clozapine		Product	Clozapine glucuronide
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	UDP-glucuronosyltransferase 1A4 (UGT1A4)					DME Info
Metabolic Type	Conjugation - Glucuronidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002836	Clozapine	Clozapine N-oxide	Oxidation - N-Oxidation	Clozapine	[1]
MR002835	Clozapine	N-desmethylclozapine	Oxidation - N-Demethylation	Clozapine	[1]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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