Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002857)
Formula
CYP2C9 ...
SVG example
Hydroxylation
Reactant Meloxicam Product 5-hydroxymethyl meloxicam
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 2A6 (CYP2A6) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 2E1 (CYP2E1) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002858 5-hydroxymethyl meloxicam 5-Carboxy meloxicam Oxidation - Oxidation Meloxicam [1], [2]
References
1 A prospective longitudinal study of growth in twin gestations compared with growth in singleton pregnancies. I. The fetal head J Ultrasound Med. 1991 Aug;10(8):439-43. doi: 10.7863/jum.1991.10.8.439.
2 Metabolism of Meloxicam in human liver involves cytochromes P4502C9 and 3A4. Xenobiotica. 1998 Jan;28(1):1-13.

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