Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002942)
Formula Reactant O-demethylated formoterol Product O-demethylated formoterol glucuronide metabolite 1
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
UDP-glucuronosyltransferase 1A8 (UGT1A8) DME Info
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002944 Formoterol O-demethylated formoterol Oxidation - O-demethylation Formoterol [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002941 O-demethylated formoterol O-demethylated formoterol glucuronide metabolite 2 Unclear Formoterol [3], [2]
References
1 Mass balance and metabolism of [(3)H]Formoterol in healthy men after combined i.v. and oral administration-mimicking inhalation Drug Metab Dispos. 1999 Oct;27(10):1104-16.
2 FDA Approved Drug Products: Perforomist? inhalation solution
3 DrugBank : Formoterol

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