Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002946)
Formula
UGT1A1 ...
SVG example
O-Glucuronidation
Reactant Formoterol Product Formoterol glucuronide metabolite 1
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
UDP-glucuronosyltransferase 1A8 (UGT1A8) DME Info
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME Info
Metabolic Type Conjugation - O-Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002945 Formoterol Formoterol deformylated metabolite Unclear Formoterol [1]
MR002947 Formoterol Formoterol glucuronide metabolite 2 Conjugation - O-Glucuronidation Formoterol [1], [2]
MR002948 Formoterol Formoterol sulfate conjugate metabolite Conjugation - Sulfation Formoterol [1]
MR002944 Formoterol O-demethylated formoterol Oxidation - O-demethylation Formoterol [1], [2]
References
1 Mass balance and metabolism of [(3)H]Formoterol in healthy men after combined i.v. and oral administration-mimicking inhalation Drug Metab Dispos. 1999 Oct;27(10):1104-16.
2 FDA Approved Drug Products: Perforomist? inhalation solution

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