Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003036)
Formula Reactant Artemisinin Product Artemisinin Metobolite M14-M22
Reactant Info Product Info
Metabolic Type Oxidation - Dihydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003035 Artemisinin 9beta-hydroxyartemisinin Unclear Artemisinin [1], [1]
MR003033 Artemisinin Artemisinin Metobolite M1-M13 Reduction - Reduction Artemisinin [2]
MR003028 Artemisinin Artemisinin Metobolite M23 Reduction - Reduction Artemisinin [2]
MR003023 Artemisinin Artemisinin Metobolite M32 Other reaction - Hydrogenation Artemisinin [2]
References
1 Microbial metabolism of artemisinin by Mucor polymorphosporus and Aspergillus niger J Nat Prod. 2002 Nov;65(11):1693-5. doi: 10.1021/np020113r.
2 A Microbial Transformation Model for Simulating Mammal Metabolism of Artemisinin Molecules. 2019 Jan 16;24(2):315. doi: 10.3390/molecules24020315.

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