Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003130)
Formula Reactant N-desalkyl delavirdine Product Delavirdine mesylate MET-15d
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003137 Delavirdine mesylate N-desalkyl delavirdine Oxidation - N-Dealkylation Delavirdine mesylate [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003128 N-desalkyl delavirdine Delavirdine mesylate MET-4a Conjugation - Sulfation Delavirdine mesylate [1]
MR003129 N-desalkyl delavirdine Delavirdine mesylate MET-4c Conjugation - Glucuronidation Delavirdine mesylate [1]
MR003131 N-desalkyl delavirdine Delavirdine mesylate MET-4d Conjugation - Sulfation Delavirdine mesylate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003132 Delavirdine mesylate MET-7 Delavirdine mesylate MET-15d Oxidation - Hydroxylation Delavirdine mesylate [1]
References
1 Identification of the metabolites of the HIV-1 reverse transcriptase inhibitor delavirdine in monkeys Drug Metab Dispos. 1997 Jul;25(7):814-27.

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