Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003157)
Formula Reactant Oxymetazoline Product Oxymetazoline metabolite M8
Reactant Info Product Info
Metabolic Type Conjugation - Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003156 Oxymetazoline Oxymetazoline metabolite M2 Oxidation - Oxidative Dehydrogenation Oxymetazoline [1]
MR003158 Oxymetazoline Oxymetazoline O-glucuronidation Conjugation - O-Glucuronidation Oxymetazoline [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003155 Oxymetazoline metabolite M8 Oxymetazoline metabolite M1 Oxidation - Hydroxylation Oxymetazoline [1]
References
1 In vitro metabolism of oxymetazoline: evidence for bioactivation to a reactive metabolite. Drug Metab Dispos. 2011 Apr;39(4):693-702.
2 Identification and characterization of oxymetazoline glucuronidation in human liver microsomes: evidence for the involvement of UGT1A9. J Pharm Sci. 2011 Feb;100(2):784-93.

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