Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003232)
Formula
SVG example
Hydrolysis
Reactant Daunorubicinol Product Daunorubicinol aglycone
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003242 Daunorubicin Daunorubicinol Reduction - Reduction Daunorubicin [1], [2], [3], [4]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003231 Daunorubicinol Deoxydaunorubicinol aglycone Hydrolysis - Hydrolysis Daunorubicin [1]
References
1 Daunorubicin metabolites in human urine J Pharmacol Exp Ther. 1975 Oct;195(1):41-9.
2 Daunorubicin and Its Active Metabolite Pharmacokinetic Profiles in Acute Myeloid Leukaemia Patients: A Pharmacokinetic Ancillary Study of the BIG-1 Trial. Pharmaceutics. 2022 Apr 5;14(4):792. doi: 10.3390/pharmaceutics14040792.
3 The electromembrane extraction of pharmaceutical compounds from animal tissues. Anal Chim Acta. 2021 Sep 8;1177:338742. doi: 10.1016/j.aca.2021.338742.
4 Electromembrane extraction of anthracyclines from plasma: Comparison with conventional extraction techniques. Talanta. 2021 Feb 1;223(Pt 2):121748. doi: 10.1016/j.talanta.2020.121748.

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