Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003298)
Formula
SVG example
Reactant Valdecoxib metabolite M4 Product Valdecoxib metabolite M6
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003295 Valdecoxib metabolite M1 Valdecoxib metabolite M4 Oxidation - Oxidation Valdecoxib [1]
MR003489 Valdecoxib metabolite M1 Valdecoxib metabolite M4 Oxidation - Oxidation Parecoxib [1], [2]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 Disposition of a specific cyclooxygenase-2 inhibitor, valdecoxib, in human Drug Metab Dispos. 2002 Sep;30(9):1013-21. doi: 10.1124/dmd.30.9.1013.

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