Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003324)
Formula
SVG example
Reactant Nimesulide metabolite M5A,5B Product Nimesulide metabolite M8
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003318 4-hydroxynimesulideM1 Nimesulide metabolite M5A,5B Unclear Nimesulide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003320 Nimesulide metabolite M5A,5B Nimesulide metabolite M2 Unclear Nimesulide [1]
MR003323 Nimesulide metabolite M5A,5B Nimesulide metabolite M5C Unclear Nimesulide [1]
MR003322 Nimesulide metabolite M5A,5B Nimesulide metabolite M7 Unclear Nimesulide [1]
MR003321 Nimesulide metabolite M5A,5B Nimesulide metabolite M9 Unclear Nimesulide [1]
References
1 Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: evidence for bioactivation Chem Res Toxicol. 2010 Nov 15;23(11):1691-700. doi: 10.1021/tx1001496.

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