Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003351)
Formula Reactant Apalutamide metabolite M9 Product Apalutamide metabolite M14
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003363 Apalutamide Apalutamide metabolite M9 Unclear Apalutamide [1]
MR003350 Apalutamide metabolite M10 Apalutamide metabolite M9 Conjugation - Cysteine Condensation Apalutamide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003344 N-desmethyl apalutamide Apalutamide metabolite M14 Unclear Apalutamide [1]
MR003347 Apalutamide metabolite M12 Apalutamide metabolite M14 Unclear Apalutamide [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003348 Apalutamide metabolite M14 Apalutamide metabolite M17 Unclear Apalutamide [1]
References
1 Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes Drug Metab Dispos. 2019 May;47(5):453-464. doi: 10.1124/dmd.118.084517.

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