Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003373)
Formula Reactant Aceclofenac Product 5-hydroxyaceclofenac
Reactant Info Product Info
Metabolic Enzyme Prostaglandin G/H synthase 1 (COX-1) DME Info
Metabolic Type Oxidation - 5-Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003371 Aceclofenac 4'-hydroxyaceclofenac Oxidation - 4'-Hydroxylation Aceclofenac [1]
MR003372 Aceclofenac Diclofenac Hydrolysis - Hydrolysis Aceclofenac [2]
References
1 DrugBank(Pharmacology-Metabolism)Aceclofenac
2 Aceclofenac in the management of inflammatory pain Expert Opin Pharmacother. 2004 Jun;5(6):1347-57. doi: 10.1517/14656566.5.6.1347.

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