Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003416)
Formula
SVG example
Hydroxylation
Reactant Sulfinpyrazone Product 4-hydroxy-sulfinpyrazone
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003413 Sulfinpyrazone p-hydroxy sulfinpyrazone Oxidation - Hydroxylation Sulfinpyrazone [1], [2]
MR003414 Sulfinpyrazone Sulfinpyrazone sulfone Oxidation - Oxidation Sulfinpyrazone [1]
MR003415 Sulfinpyrazone Sulphide Oxidation - Oxidation Sulfinpyrazone [2]
References
1 Metabolism of sulfinpyrazone sulfide and sulfinpyrazone by human liver microsomes and cDNA-expressed cytochrome P450s. Drug Metab Dispos. 2001 May;29(5):701-11.
2 Species differences in the disposition and metabolism of sulfinpyrazone Xenobiotica. 1981 Aug;11(8):559-68. doi: 10.3109/00498258109045867.

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