Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003442)
Formula
SVG example
N-dealkylation
Reactant Gilteritinib Product Gilteritinib metabolite M16
Reactant Info Product Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003439 Gilteritinib Gilteritinib metabolite M10 Oxidation - N-dealkylation Gilteritinib [1]
MR003443 Gilteritinib Gilteritinib metabolite M14 Unclear Gilteritinib [1]
MR003445 Gilteritinib Gilteritinib metabolite M17 Oxidation - N-dealkylation Gilteritinib [1]
MR003444 Gilteritinib Gilteritinib metabolite M8 Unclear Gilteritinib [1]
MR003446 Gilteritinib Gilteritinib metabolite M9 Unclear Gilteritinib [1]
References
1 Pharmacokinetic Profile of Gilteritinib: A Novel FLT-3 Tyrosine Kinase Inhibitor Clin Pharmacokinet. 2020 Oct;59(10):1273-1290. doi: 10.1007/s40262-020-00888-w.

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