Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003498)
Formula Reactant Cephaeline Product Cephaeline 6'-O-glucuronide metabolite
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003497 Ipecac Cephaeline Oxidation - Demethylation Ipecac [1], [2]
References
1 Metabolism of ipecac alkaloids cephaeline and emetine by human hepatic microsomal cytochrome P450s, and their inhibitory effects on P450 enzyme activities. Biol Pharm Bull. 2001 Jun;24(6):678-82.
2 Biotransformation of the ipecac alkaloids cephaeline and emetine from ipecac syrup in rats Eur J Drug Metab Pharmacokinet. 2002 Jan-Mar;27(1):29-35. doi: 10.1007/BF03190402.

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