Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003529)
Formula Reactant 4-hydroxytamoxifen sulfate Product Endoxifen
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 1A1 (SULT1A1) DME Info
Sulfotransferase 1E1 (SULT1E1) DME Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003528 4-hydroxytamoxifen 4-hydroxytamoxifen sulfate Conjugation - Sulfation Tamoxifen citrate [1]
MR003518 Endoxifen 4-hydroxytamoxifen sulfate Conjugation - Sulfation Tamoxifen citrate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005295 Cis-4-hydroxytamoxifen Endoxifen Oxidation - N-demethylation Cis-4-hydroxytamoxifen [2]
MR003530 4-hydroxytamoxifen Endoxifen Conjugation - Sulfation Tamoxifen citrate [1]
MR003516 N-Desmethyltamoxifen Endoxifen Oxidation - 4-Hydroxylation Tamoxifen citrate [1]
References
1 PharmGKB:Tamoxifen citrate
2 Tamoxifen dose and serum concentrations of tamoxifen and six of its metabolites in routine clinical outpatient care

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.