Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003642)
Formula
SVG example
Oxidationn
Reactant 11-OH-THC Product THC-COOH
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006696 Dronabinol 11-OH-delata-Tetrahydrocannabinol Oxidation - Aliphatic hydroxylation Dronabinol [1], [2]
MR003641 THC 11-OH-THC Oxidation - Hydrolyzationn GW-1000 [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003643 THC-COOH THC-COOH-glu Unclear GW-1000 [3]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.
3 Techniques and technologies for the bioanalysis of Sativex?, metabolites and related compounds

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.