Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003907)
Formula Reactant GS-9883 Product GS-9883 Metabolite M22
Reactant Info Product Info
Metabolic Type Reduction - Defluorination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003911 GS-9883 GS-9883 Metabolite M15 Conjugation - Glucuronidation GS-9883 [1]
MR003912 GS-9883 GS-9883 Metabolite M21 Oxidation - Oxidationn GS-9883 [1]
MR003909 GS-9883 GS-9883 Metabolite M23 Oxidation - Oxidationn GS-9883 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003908 GS-9883 Metabolite M22 GS-9883 Metabolite M9 Conjugation - Cysteine conjugation GS-9883 [1]
References
1 Human and nonclinical disposition of [(14)C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection

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