Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003922)
Formula Reactant M/Z457 Product M/Z458
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003921 H3B-6545 M/Z457 Oxidation - N-dealkylation H3B-6545 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003923 M/Z458 M/Z472 Unclear H3B-6545 [1]
References
1 Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERalpha covalent antagonist (SERCA). Cancer Chemother Pharmacol. 2019 Jan;83(1):151-160.

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