Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004052)
Formula Reactant SSR-97193 Product SSR-97193 Metabolite D
Reactant Info Product Info
Metabolic Type Oxidation - N-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004050 SSR-97193 4-amino-7 chloroquinoline Unclear SSR-97193 [1]
MR004048 SSR-97193 7-chloro-4-(2-hydroxymethylferrocenylmethyl) aminoquinoline Unclear SSR-97193 [1]
MR004046 SSR-97193 Mono-N-demethyl ferroquine Unclear SSR-97193 [1]
MR004051 SSR-97193 SSR-97193 Metabolite E Oxidation - Hydrolyzationn SSR-97193 [1]
References
1 In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum. Drug Metab Dispos. 2006 Apr;34(4):667-82.

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