Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004240)
Formula
SVG example
Hydrolyzation
Reactant Esculin Product Esculetin
Reactant Info Product Info
Metabolic Enzyme Acid beta-glucosidase (GBA1) DME Info
Metabolic Type Hydrolysis - Hydrolyzation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004239 Esculin Esculetin beta-glucosidases Hydrolysis - Hydrolyzation Esculin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009399 CPA-926 Esculetin Unclear - Unclear CPA-926 [2]
References
1 A prodrug approach to the use of coumarins as potential therapeutics for superficial mycoses. PLoS One. 2013 Nov 18;8(11):e80760.
2 Esculetin (dihydroxycoumarin) inhibits the production of matrix metalloproteinases in cartilage explants, and oral administration of its prodrug, CPA-926, suppresses cartilage destruction in rabbit experimental osteoarthritis

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